Ku80 Rabbit pAb

Predicted to enable several functions, including nucleic acid binding activity, protein C-terminus binding activity, and ubiquitin protein ligase binding activity. Predicted to contribute to 5'-deoxyribose-5-phosphate lyase activity and double-stranded telomeric DNA binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor, hematopoietic stem cell differentiation, and positive regulation of neurogenesis. Located in cytoplasm and nucleus. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease and multiple myeloma. Orthologous to human XRCC5 (X-ray repair cross complementing 5). Synonyma: Ku80, Ku86, CTC85, CTCBF