IL33 Rabbit pAb

Enables cytokine activity and interleukin-33 receptor binding activity. Involved in several processes, including interleukin-33-mediated signaling pathway, microglial cell activation involved in immune response, and regulation of gene expression. Acts upstream of or within several processes, including negative regulation of macrophage proliferation, positive regulation of cellular defense response, and positive regulation of macromolecule metabolic process. Located in nucleus. Is expressed in several structures, including adrenal gland, alimentary system, genitourinary system, nervous system, and sensory organ. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in candidiasis, inflammatory bowel disease, and peptic ulcer disease. Orthologous to human IL33 (interleukin 33).