ABflo® 488 Rabbit anti-Mouse/Rat CD27 mAb

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in negative regulation of apoptotic process and positive regulation of JNK cascade. Acts upstream of or within negative regulation of T cell apoptotic process. Located in external side of plasma membrane. Is expressed in several structures, including femur, hemolymphoid system, intestine, pituitary gland, and reproductive system. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2. Orthologous to human CD27 (CD27 molecule). Synonyma: S152, Tp55, Tnfrsf7