Bcl-2 Rabbit mAb

Enables BH domain binding activity. Involved in several processes, including response to peptide, response to purine-containing compound, and response to vitamin. Located in cytosol, mitochondrial crista, and perinuclear region of cytoplasm. Used to study several diseases, including brain ischemia (multiple), end stage renal disease, gastric ulcer, intestinal disease (multiple), and status epilepticus. Biomarker of several diseases, including abdominal obesity-metabolic syndrome 1, brain disease (multiple), hypertension (multiple), intrinsic cardiomyopathy (multiple), and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple), hematologic cancer (multiple), intracranial aneurysm, prostate cancer, and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator).