ABflo® 488 Rabbit anti-Mouse CD182/CXCR2 mAb

Enables chemokine receptor activity. Acts upstream of or within negative regulation of apoptotic process. Predicted to be located in several cellular components, including cell surface, mast cell granule, and mitotic spindle. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system, central nervous system, embryo mesenchyme, epithelium, and heart. Human ortholog(s) of this gene implicated in IgA glomerulonephritis, acute pyelonephritis, end stage renal disease, and urinary bladder cancer. Orthologous to human CXCR2 (C-X-C motif chemokine receptor 2).