ABflo® 488 Rabbit anti-Mouse I-A mAb

Enables several functions, including peptide antigen binding activity, protein antigen binding activity, and toxic substance binding activity. Involved in several processes, including B cell affinity maturation, cellular response to interferon-gamma, and positive regulation of T-helper 1 type immune response. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and immune response. Located in Golgi apparatus, endosome, and external side of plasma membrane. Is integral component of membrane. Part of MHC class II protein complex. Is expressed in lung, metanephros, and thymus primordium. Orthologous to human HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2). Synonyma: H-2I, I-Ad, -Ed, I-Eb and I-Ek MHC class II alloantigens, Ia Ag, MHC II