ABflo® 647 Rabbit anti-Mouse CD204 mAb

Enables amyloid-beta binding activity, cargo receptor activity, and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis, positive regulation of cholesterol storage, and positive regulation of macrophage derived foam cell differentiation. Acts upstream of or within establishment of localization in cell and lipoprotein transport. Located in plasma membrane. Is expressed in several structures, including alimentary system, early conceptus, limb, neural tube, and reproductive system. Human ortholog(s) of this gene implicated in Barrett's esophagus, arteriosclerosis, and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1). Synonyma: MSR, SR-A, Scvr, MRS-A, MSR-A, SR-AI, SR-AII, Scara1