[KO Validated] HIF1AN/FIH-1 Rabbit mAb

Enables several functions, including 2-oxoglutarate-dependent dioxygenase activity, NF-kappaB binding activity, and transition metal ion binding activity. Involved in several processes, including negative regulation of Notch signaling pathway, negative regulation of transcription from RNA polymerase II promoter in response to hypoxia, and protein hydroxylation. Located in cytosol, nucleoplasm, and perinuclear region of cytoplasm. Colocalizes with nucleus. Synonyma: FIH1