Heme Oxygenase 1 Rabbit mAb

Predicted to enable several functions, including heme binding activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, and protein homodimerization activity. Acts upstream of or within several processes, including cellular response to cadmium ion, cellular response to cisplatin, and regulation of macroautophagy. Located in nucleus. Is active in cytosol. Is expressed in several structures, including alimentary system, central nervous system, genitourinary system, respiratory system, and sensory organ. Used to study hemochromatosis and malaria. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple), cerebrovascular disease (multiple), factor VIII deficiency, lung disease (multiple), and sickle cell anemia. Orthologous to human HMOX1 (heme oxygenase 1).