ABflo® 488 Rabbit anti-Mouse CD21/CD35 mAb

Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide, immunoglobulin mediated immune response, and skeletal system development. Located in external side of plasma membrane. Is expressed in several structures, including brain, hemolymphoid system, liver, placenta, and yolk sac. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7, nasopharynx carcinoma, and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2). Synonyma: Cr1, C3DR, CD21, CD35, Cr-1, Cr-2