IGFBP3 Rabbit pAb

Enables fibronectin binding activity and insulin-like growth factor binding activity. Involved in osteoblast differentiation. Acts upstream of or within several processes, including positive regulation of signal transduction, regulation of glucose metabolic process, and type B pancreatic cell proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system, brain, early embryo, gonad, and limb. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease, Turner syndrome, diabetes mellitus (multiple), prostate cancer, and transitional cell carcinoma. Orthologous to human IGFBP3 (insulin like growth factor binding protein 3).