TFEB Rabbit pAb

Enables DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding activity, and protein heterodimerization activity. Involved in several processes, including defense response to Gram-negative bacterium, embryonic placenta development, and positive regulation of transcription by RNA polymerase II. Acts upstream of or within lysosome organization. Located in cytoplasm. Part of transcription regulator complex. Colocalizes with nucleus. Is expressed in several structures, including cardiovascular system, central nervous system, early conceptus, genitourinary system, and gut gland. Orthologous to human TFEB (transcription factor EB). Synonyma: Tcfeb, bHLHe35