ZO-1 Rabbit mAb

Enables connexin binding activity and protein domain specific binding activity. Involved in several processes, including ameloblast differentiation, negative regulation of stress fiber assembly, and positive regulation of sprouting angiogenesis. Acts upstream of or within blastocyst formation and sensory perception of sound. Located in several cellular components, including apicolateral plasma membrane, bicellular tight junction, and intercellular canaliculus. Part of protein-containing complex. Is expressed in several structures, including alimentary system, central nervous system, early conceptus, genitourinary system, and sensory organ. Orthologous to human TJP1 (tight junction protein 1).