TNF-α Rabbit mAb

Enables tumor necrosis factor receptor binding activity. Involved in several processes, including negative regulation of transport, positive regulation of cell communication, and positive regulation of macromolecule biosynthetic process. Acts upstream of or within positive regulation of interleukin-6 production. Located in external side of plasma membrane, extracellular space, and neuronal cell body. Is active in extracellular region. Used to study several diseases, including cerebrovascular disease (multiple), liver disease (multiple), peptic esophagitis, perinatal necrotizing enterocolitis, and periventricular leukomalacia. Biomarker of several diseases, including artery disease (multiple), brain disease (multiple), congestive heart failure (multiple), liver disease (multiple), and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple), eye disease (multiple), liver disease (multiple), lung disease (multiple), and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor).