ADAMTS13 Rabbit mAb

This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. Synonyma: VWFCP, C9orf8, vWF-CP, ADAM-TS13, ADAMTS-13, ADAMTS13