EDG1/HEXIM1 Rabbit mAb

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. Synonyma: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, EDG1/HEXIM1