SERPINB1 Rabbit pAb

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. Synonyma: EI, LEI, PI2, MNEI, PI-2, HEL57, M/NEI, ELANH2, HEL-S-27, SERPINB1