KDM4B/JMJD2B Rabbit mAb

Enables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability, breast cancer, colorectal cancer, malignant peripheral nerve sheath tumor, and stomach cancer. Biomarker of several diseases, including alopecia areata, lung cancer, medulloblastoma, prostate cancer, and stomach cancer.