BAF60a Rabbit pAb

Predicted to enable several functions, including chromatin binding activity, molecular adaptor activity, and transcription coregulator activity. Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation, nucleosome disassembly, and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization and nervous system development. Part of SWI/SNF complex, nBAF complex, and npBAF complex. Is expressed in several structures, including central nervous system, dorsal root ganglion, early conceptus, genitourinary system, and retina layer. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome. Orthologous to human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1).