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Human Trop-2 Monoclonal Antibody

Human Trop-2 Monoclonal Antibody
Poznámka k dopravě
Dopravné k jednorázové objednávce činí 2.000 Kč, které rozpočítáváme při fakturaci do cen za zboží. V rámci snížení nákladů na dopravu se snažíme konsolidovat objednávky tak, aby se tato suma rozdělila mezi maximum zákazníků. Před objednáním u dodavatele jsou všichni zákazníci vždy předem informovaní o aktuální výši dopravy.
Human Trop-2 Monoclonal Antibody
Sacituzumab govitecan is a Trop-2-directed antibody and topoisomerase inhibitor drug conjugate used ...
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Cena bez DPH: 7 800,00Kč
  • Výrobce: ABclonal
  • Kód výrobce: ABC-YR0018

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Dotaz na zboží

Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

Sacituzumab govitecan is a Trop-2-directed antibody and topoisomerase inhibitor drug conjugate used for the treatment of metastatic triple-negative breast cancer and metastatic urothelial cancer. Triple-negative breast cancer is a type of breast cancer that tests negative for estrogen receptors, progesterone receptors and human epidermal growth factor receptor 2 (HER2) protein. Therefore, triple-negative breast cancer does not respond to hormonal therapy medicines or medicines that target HER2.Sacituzumab govitecan is a conjugate of the humanized anti-Trop-2 monoclonal antibody linked with SN-38, the active metabolite of irinotecan. Each antibody having on average 7.6 molecules of SN-38 attached. SN-38 is too toxic to administer directly to patients, but linkage to an antibody allows the drug to specifically target cells containing Trop-2. Synonyma: TACSTD2, EGP1, GP50, M1S1, EGP-1, TROP2, GA7331, GA733-1
Technické specifikace
Doprava a skladování Store at 2 - 8℃. 2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)
Vlastnosti
Aplikace ELISA,neutralization,functional assays such as bioanalytical PK and ADA assays,and those assays for studying biological pathways
Fluorochrom <5% Determined by SECP
Klon Biosimilar
Předpokládaná křížová reaktivita <1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Původ 0.2 μm filtration
Specifita Sacituzumab Biosimilar
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