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Human IL4R alpha Monoclonal Antibody

Human IL4R alpha Monoclonal Antibody
Poznámka k dopravě
Dopravné k jednorázové objednávce činí 2.000 Kč, které rozpočítáváme při fakturaci do cen za zboží. V rámci snížení nákladů na dopravu se snažíme konsolidovat objednávky tak, aby se tato suma rozdělila mezi maximum zákazníků. Před objednáním u dodavatele jsou všichni zákazníci vždy předem informovaní o aktuální výši dopravy.
Human IL4R alpha Monoclonal Antibody
What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin...
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  • Výrobce: ABclonal
  • Kód výrobce: ABC-YR0148

Dostupné možnosti

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Dotaz na zboží

Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. Dupilumab binds to the alpha subunit of the interleukin-4 receptor (IL-4Ra), making it a receptor antagonist. Through blockade of IL-4Ra, dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab biosimilar uses the same protein sequences as the therapeutic antibody dupilumab. Synonyma: CD124, IL-4RAA, IL4R
Technické specifikace
Doprava a skladování Store at 2 - 8℃. 2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)
Vlastnosti
Aplikace ELISA,neutralization,functional assays such as bioanalytical PK and ADA assays,and those assays for studying biological pathways
Fluorochrom <5% Determined by SECP
Klon Biosimilar
Předpokládaná křížová reaktivita <1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Původ 0.2 μm filtration
Specifita Dupilumab Biosimilar
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