Anti-RASSF1 (NORE1) Antibody

RASSF5 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat RASSF5 and is antigen affinity purified. It is great for use in WB. RASSF1A, a new tumor-suppressor gene located at 3p21.3 is frequently inactivated by promoter region hypermethylation in a variety of human cancers including lung, breast, kidney and neuroblastoma. Another member of the RASSF1 gene family, Ras effector NORE1, which is structurally related to RASSF1, can also mediate a Ras-dependent apoptosis. Moreover, an analysis of NORE1 protein expression showed that it is frequently down-regulated in lung tumor cell lines and primary lung tumors.