CD52 FITC

Clone CF-1D12 recognizes human CD52, a 21-28 kDa glycoprotein whose C-terminus is glycophosphatidylinositol (GPI) anchored within the membrane. It is also known as Cambridge pathology antigen 1 (CAMPATH-1). Binding of CF-1D12 with CD52 induces a potent complement-mediated cytolytic immune response of matured lymphocytes. It is widely expressed on the surface of thymocytes and mature lymphocytes, on monocytes, dendritic cells, eosinophils and epithelial cells of the epididymis and seminal vesicles but not on neutrophils, plasma cells, platelets or erythrocytes.