CD117 Unconjugated

CD117, also known as c-Kit or the stem cell factor receptor (SCFR), is a 145-kDa transmembrane glycoprotein belonging to the receptor tyrosine kinase family. It serves as the receptor for stem cell factor (SCF), also referred to as steel factor or mast cell growth factor. CD117 is characteristically expressed on hematopoietic stem and progenitor cells—including multipotent stem cells and precursors committed to myeloid, erythroid, and early lymphoid lineages—as well as mast cells, thymocytes, hepatocytes, histiocytes, and many acute myeloid leukemia (AML) cells.