SW-1116 Cells

The cell line was isolated from colorectal adenocarcinoma tissue by Leibovitz et al. in 1976. They are positive for keratin by immunoperoxidase staining, but negative for CSAp (CSAp-) and colon antigen 3. The oncogenes c-myc, K-ras, H-ras, myb, sis and fos oncogenes are expressed, N-myc and N-ras expression was not observed. The tumor specific nuclear matrix proteins CC-4, CC-5 and CC-6 are expressed.