G361 Cells

G361 is a human melanoma cell line derived from a metastatic site in the skin of an adult patient. This cell line exhibits melanin production, which is a characteristic feature of melanocytes and melanoma cells. G361 cells are known for their epithelial-like morphology and are extensively used in research focused on skin cancer, particularly melanoma. The cells are valuable for studying the biology and pathogenesis of melanoma, including cell proliferation, migration, and invasion. Additionally, they serve as a useful model for drug screening and for understanding the mechanisms of resistance to chemotherapy in melanoma. The G361 cell line has been used to explore the genetic and molecular underpinnings of melanoma. It has been instrumental in studies investigating the role of various oncogenes and tumor suppressor genes in cancer progression. For instance, research utilizing G361 cells has contributed to insights into the MAPK/ERK pathway, which is often dysregulated in melanoma. These cells are also commonly used in assays to evaluate the efficacy of new therapeutic agents, making them crucial for translational research and the development of targeted treatments for melanoma. Skin cancer cell lines, Skin, Melanoma, Growth Conditions: Adherent, Biosafety level: BSL 1