A3 Cells

A3 cells are human T lymphoblasts derived from the Jurkat cell line obtained from the laboratory of Gerald Crabtree at Stanford University. These cells possess a lymphoblast morphology, grow in suspension and are highly relevant in studying acute T cell leukaemia, 3D cell culture applications, immune system disorder research, and immunology. These cells are derived from the Jurkat cell line, which was treated with Fas Antibody to obtain a low spontaneous resistance rate to Fas-mediated apoptosis. This characteristic makes A3 cells highly valuable for investigating immune system dysregulation and identifying potential therapeutic targets.