L6565 Cells

L6565 cells were derived from pancreatic suspensions of splenocytes from L6565 leukemia mice. The chromosomal count ranged from 38 to 144. Electron microscopic observations revealed that the clonal L6565 cells had well-defined nuclei and an abundance of organelles and Class A and Class C viral particles in the cytoplasm. The oncogenes c-myc and c-fos were overexpressed in these cells. The L6565 cell clone is an RNA virus-containing lymphoblastic leukemia stem cell line. It has passed the mycoplasma detection test in this library. The significance of the L6565 cell line lies in its provision of standardized experimental cell resources and associated technical support for research in the fields of life sciences and biotechnology. These cells can be crucial for understanding the molecular mechanisms of leukemia, particularly the role of viral particles and oncogene expression in leukemogenesis. Additionally, they serve as a valuable tool for drug testing and development, allowing researchers to explore potential therapeutic strategies for leukemia and other related disorders.