BHK-21 clone 13 Cells

BHK-21 clone 13 cells, a subline of the baby hamster kidney (BHK) cell line, have become a pivotal model in virology and molecular biology research due to their robustness, ease of culture, and high transfection efficiency. The cells are used in the study of virus infection, antigen production, and recombinant protein synthesis. BHK-21 cells are susceptible to a broad range of viruses, including alphaviruses, flaviviruses, and rhabdoviruses, which has made them an invaluable tool in the study of viral replication, pathogenesis, and the development of viral vectors for gene therapy and vaccines. Their utility in viral research is further enhanced by their ability to support high-titer virus production, facilitating the study of virus-host interactions and the screening of antiviral compounds. BHK-21 cells are further used in recombinant protein production because of their high transfection efficiency. This feature enables their utility for the production of therapeutic proteins, antibodies, and for the development of novel biotechnological products. BHK-21 cells also serve as a model for studying cellular processes such as cell adhesion, signal transduction, and apoptosis. This has implications for understanding disease mechanisms and testing the cellular response to various stimuli, including drugs and environmental factors. In summary, BHK-21 clone 13 cells serve as a critical tool in the fields of virology, molecular biology, and biotechnology.