Kdm6b Rabbit pAb

Enables beta-catenin binding activity, histone H3-tri/di-methyl-lysine-27 demethylase activity, and sequence-specific DNA binding activity. Involved in several processes, including histone H3-K27 demethylation, mesodermal cell differentiation, and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to hydrogen peroxide, histone demethylation, and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including brain, gut, liver, metanephros, and olfactory epithelium. Orthologous to human KDM6B (lysine demethylase 6B).