Papillary renal cell carcinoma Rabbit pAb

This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X,1)(p11,q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.