IL18 Rabbit pAb

Enables cytokine activity. Involved in lipid homeostasis, positive regulation of cell differentiation, and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including interleukin-18-mediated signaling pathway, positive regulation of NIK/NF-kappaB signaling, and positive regulation of interferon-gamma production. Located in extracellular space. Is expressed in several structures, including back skin, dorsal aorta, gut, lymphatic system, and reproductive system. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease, allergic rhinitis, autoimmune disease (multiple), biliary atresia, and hepatitis B. Orthologous to human IL18 (interleukin 18).