MAPT Rabbit pAb

Enables DNA binding activity, microtubule binding activity, and protein kinase binding activity. Involved in negative regulation of tubulin deacetylation, regulation of cellular response to heat, and regulation of response to DNA damage stimulus. Acts upstream of or within several processes, including adult walking behavior, generation of neurons, and transport along microtubule. Located in several cellular components, including cytoskeleton, glial cell projection, and postsynaptic density. Is expressed in several structures, including gut, nervous system, sensory organ, smooth muscle tissue, and urinary system. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in dementia (multiple), neurodegenerative disease (multiple), progressive supranuclear palsy, and temporal lobe epilepsy. Orthologous to human MAPT (microtubule associated protein tau).