ICOS/CD278 Rabbit mAb

Predicted to be involved in T cell costimulation, T cell tolerance induction, and cell-cell adhesion. Located in external side of plasma membrane. Is integral component of plasma membrane. Used to study common variable immunodeficiency. Human ortholog(s) of this gene implicated in celiac disease, common variable immunodeficiency, and immunoglobulin alpha deficiency. Orthologous to human ICOS (inducible T cell costimulator).