VEGFR2/KDR/Flk-1/CD309 Rabbit pAb

Enables growth factor binding activity and vascular endothelial growth factor-activated receptor activity. Involved in several processes, including circulatory system development, peptidyl-tyrosine autophosphorylation, and positive regulation of vasculogenesis. Acts upstream of or within several processes, including animal organ development, positive regulation of cell population proliferation, and vasculature development. Located in several cellular components, including cell junction, endosome, and external side of plasma membrane. Is expressed in several structures, including alimentary system, cardiovascular system, central nervous system, extraembryonic component, and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including adhesions of uterus, artery disease (multiple), gastrointestinal system cancer (multiple), macular degeneration (multiple), and pancreatic cancer (multiple). Orthologous to human KDR (kinase insert domain receptor).