Fibronectin Rabbit pAb

Enables peptidase activator activity. Acts upstream of or within several processes, including calcium-independent cell-matrix adhesion, cell-substrate junction assembly, and positive regulation of axon extension. Located in apical plasma membrane and basement membrane. Is expressed in several structures, including alimentary system, cardiovascular system, egg cylinder, embryo mesenchyme, and genitourinary system. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis, membranoproliferative glomerulonephritis, and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1).