ABflo® 488 Rabbit anti-Mouse CD88/C5aR mAb

Enables complement component C5a receptor activity. Involved in several processes, including astrocyte activation, positive regulation of vascular endothelial growth factor production, and regulation of granulocyte chemotaxis. Acts upstream of or within defense response to Gram-positive bacterium, neutrophil chemotaxis, and response to peptidoglycan. Predicted to be located in several cellular components, including apical part of cell, basolateral plasma membrane, and cell surface. Predicted to be active in plasma membrane. Is expressed in several structures, including brain, liver, neural ectoderm, and sensory organ. Orthologous to several human genes including OPRPN (opiorphin prepropeptide). Synonyma: C5aR, C5r1, Cd88, D7Msu1