MYH6/Aα-MHC Rabbit mAb

Enables microfilament motor activity. Involved in cardiac muscle contraction. Acts upstream of or within several processes, including adult heart development, regulation of heart contraction, and striated muscle cell development. Located in Z disc and stress fiber. Part of myosin complex. Is expressed in several structures, including brown fat, embryo mesenchyme, great vessel of heart, heart, and skeletal musculature. Used to study dilated cardiomyopathy, dilated cardiomyopathy 1EE, and hypertrophic cardiomyopathy 14. Human ortholog(s) of this gene implicated in atrial heart septal defect (multiple), heart conduction disease (multiple), and intrinsic cardiomyopathy (multiple). Orthologous to human MYH6 (myosin heavy chain 6).