PE Rabbit anti-Rat IFN-gamma mAb

Interferon-gamma (IFN-γ) is a potent pleiotropic cytokine primarily secreted by activated NK cells and T lymphocytes. Initially characterized based on its antiviral activity, IFN-γ also exhibits antiproliferative, immunoregulatory, and pro-inflammatory properties. It can upregulate the expression of both MHC class I and class II molecules on antigen-presenting cells. The DB-1 antibody reacts with rat and mouse interferon-gamma (IFN-γ) and is capable of neutralizing the biological activity of both native and recombinant IFN-γ. The DB-1 antibody has been well-characterized in applications including ELISPOT, ELISA, intracellular staining, Western blot, immunohistochemistry (IHC), and neutralization assays (both in vitro and in vivo).