[KO Validated] LAMP2 Rabbit mAb

Enables protein domain specific binding activity. Involved in several processes, including autophagosome maturation, protein stabilization, and protein targeting to lysosome involved in chaperone-mediated autophagy. Acts upstream of or within muscle cell cellular homeostasis. Located in bounding membrane of organelle. Is active in lysosome. Is expressed in several structures, including central nervous system, egg cylinder, heart valve, oocyte, and sensory organ. Used to study Danon disease. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Orthologous to human LAMP2 (lysosomal associated membrane protein 2).