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In vivo Grade Recombinant Anti-mouse CD28 Monoclonal Antibody, Syrian Hamster IgG2 (Clone: 37.51)

In vivo Grade Recombinant Anti-mouse CD28 Monoclonal Antibody, Syrian Hamster IgG2 (Clone: 37.51)
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In vivo Grade Recombinant Anti-mouse CD28 Monoclonal Antibody, Syrian Hamster IgG2 (Clone: 37.51)
The in vivo grade recombinant hamster monoclonal antibody (clone: 37.51) specifically binds to the m...
5 401,00Kč
Cena bez DPH: 4 463,64Kč
  • Výrobce: ABclonal
  • Kód výrobce: ABC-YR0385

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Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

The in vivo grade recombinant hamster monoclonal antibody (clone: 37.51) specifically binds to the mouse CD28 protein. CD28 is a critical costimulatory receptor belonging to the immunoglobulin superfamily. Upon binding to its ligands CD80 (B7-1) and CD86 (B7-2)—expressed on antigen-presenting cells (APCs)—CD28 triggers intracellular signaling cascades that promote T cell proliferation, cytokine production, and the survival of activated T cells. Dysregulation of CD28 signaling is linked to autoimmune diseases, immune deficiency, and impaired antitumor immunity, making it a central target for studying immune activation and modulation in murine models. Synonyma:
Technické specifikace
Doprava a skladování Store at 2 - 8℃. 2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)
Vlastnosti
Aplikace ELISA,flow cytometry,neutralization,functional assays such as bioanalytical PK and ADA assays,and those assays for studying biological pathways affected by the mouse CD28 protein.
Fluorochrom <5% Determined by SECP
Klon Biosimilar
Předpokládaná křížová reaktivita <1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Původ 0.2 μm filtration
Specifita 37.51
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