CD16 PE

Alternative clone name HuNK2, the clone C-4H1G, a mouse monoclonal antibody binds to the 50-65 kDa transmembrane protein of IgG FcγRIII known as CD16, a surface antigen commonly associated with human NK cells. In addition to surface expression on NK cells, CD16 is expressed on activated monocytes, macrophages, neutrophils, and placental trophoblasts in humans. C-4H1G has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.