CD18 PE

CD18 is a type I transmembrane glycoprotein with a molecular weight of approximately 90–95 kDa. It is the β2 integrin subunit and is also referred to as the LFA-1 β chain. CD18 forms non-covalent heterodimers with the α integrin subunits CD11a, CD11b, or CD11c. This molecule is broadly expressed on leukocytes, including lymphocytes and monocytes, with lower expression levels on granulocytes. CD18, together with its associated α subunits, mediates cell–cell adhesion and participates in intracellular signaling pathways essential for immune and inflammatory responses in hematopoietic cells.