CD147 iFluor488

The clone C147-8D6, a mouse monoclonal antibody, selectively binds to the human 50-60-kDa glycoprotein of the immunoglobulin superfamily, also known as extracellular matrix metalloproteinase inducer (EMMPRIN). CD147 broadly expressed on haemopoietic cell lines and non-hematopoietic origin. Its expression on specific cell types may be regulated by cytokines. CD147 plays a role in embryonal blood-brain barrier development and a role in integrin-mediated adhesion in brain endothelia.