CD79a APC

CD79a, also referred to as mb-1 or Iga, is a 47 kDa type I transmembrane protein and a member of the immunoglobulin superfamily. It forms a disulfide-linked heterodimer with CD79b (also known as B29), and this complex associates with surface immunoglobulin on B cells to constitute the B cell antigen receptor (BCR) complex. CD79a is present throughout B cell development, from the early pre-B stage to plasma cells. Additionally, low levels of CD79a expression have been observed in certain T cell and myeloid precursors. Functionally, CD79a is involved in both the transport of IgM to the cell surface and in signal transduction triggered by BCR engagement.