HCC366 Cells

HCC366 is a cell line derived from a non-small cell lung cancer (NSCLC) specifically categorized as lung adenocarcinoma. This cell line was established from the malignant pleural effusion of an 80-year old female patient. HCC366 is particularly noted for its characteristic expression of mutations in key oncogenes and tumor suppressor genes, which makes it a valuable model for studying the molecular mechanisms of lung adenocarcinoma and for testing therapeutic strategies targeted at these genetic alterations. In research contexts, HCC366 has been utilized to explore the efficacy of various chemotherapeutic agents, as well as to understand resistance mechanisms to treatment. This cell line has also contributed to the investigation of the interaction between genetic mutations and response to targeted therapies, offering insights that are crucial for the development of personalized medicine approaches in lung cancer. Studies using HCC366 can help elucidate the biological behaviors typical of lung adenocarcinomas, such as cell proliferation, migration,