Mv.1.Lu Cells

The Mv.1.Lu cell line, also known as CCL 64, originates from the lung tissue of a fetal mink (Mustela vison). It is an epithelial-like cell line known for its flat, contact-inhibited growth in monolayer cultures, exhibiting a regular polygonal morphology. This cell line has been widely utilized in virological studies due to its broad permissivity for various mammalian Type C viruses, including murine and feline sarcoma viruses, making it a preferred system for focus formation assays and viral transformation studies. This cell line's ability to support viral replication and transformation has made it an essential tool in understanding viral pathogenesis and host-pathogen interactions. Mv.1.Lu cells are also used in pulmonary physiology research, benefiting from their origin in lung tissue. Studies on their growth characteristics, including their response to various media and culture conditions, have underscored their adaptability and stability in laboratory settings.