CHO-HER2 Cells

Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The CHO-HER2-Medium-high cell line is a stable recombinant CHO (Chinese Hamster Ovary) cell line that expresses the HER2 receptor at a medium-high level, approximately 13,000 molecules per cell. This cell line was developed using an innovative landing pad technology, ensuring the HER2 gene's targeted integration at a specific, pre-validated genomic locus. HER2, also known as ERBB2 or CD340, is a member of the epidermal growth factor receptor (EGFR) family and plays a critical role in regulating cell growth and differentiation. It is a significant biomarker and target in breast and ovarian cancers, where its overexpression is associated with increased tumor aggressiveness and poorer patient outcomes. The expression of CXCR7 in this cell line was confirmed using flow cytometry.