B16-F1 Cells

The B16-F1 cell line, derived from the parent B16-F0 mouse melanoma cells, is characterized by a fibroblast-like morphology, comprising a mixture of spindle-shaped and epithelial-like cells. This cell line is part of a family of melanoma cell lines, including B16-F10 and B16-BL6, which were developed through selective procedures to enhance specific characteristics. B16-F1, obtained through a one-time selective process, serves as a vital model due to its stable properties and reproducible behavior in experimental setups. Compared to its sister cell lines, B16-F10 and B16-BL6, which exhibit higher metastatic potential and invasive activity, B16-F1 has a relatively low metastatic ability. This makes it particularly useful for studies focused on the early stages of cancer metastasis and the efficacy of anti-cancer therapies. The B16-F1 cell line's consistent behavior, even after multiple subcultures, ensures reliable results, making it an invaluable tool in cancer research, immunotherapy assessments, and the study of tumor progression. Mouse cell lines, Skin, Melanoma, Growth Conditions: Adherent, Biosafety level: BSL 1